Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 6/20 | 0.43 |
| ▸ | QPCT | Q16769 | 3/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704789 | 0.97 | RAB9A (0.47) | RAB9AKDM4EQPCTLQPCTSLC5A2 | |
| SCHEMBL9702829 | 0.93 | RAB9A (0.51) | RAB9AKDM4EQPCTLQPCTSLC5A2 | |
| SCHEMBL9702825 | 0.90 | RAB9A (0.47) | RAB9AKDM4EQPCTLQPCTALDH1A1 | |
| SCHEMBL9702717 | 0.89 | RAB9A (0.60) | RAB9AKDM4EQPCTLQPCTALDH1A1 | |
| SCHEMBL9702831 | 0.88 | RAB9A (0.50) | RAB9AKDM4EQPCTLQPCTSLC5A2 | |
| SCHEMBL9702454 | 0.88 | RAB9A (0.54) | RAB9AKDM4EQPCTLQPCTALDH1A1 | |
| SCHEMBL9704028 | 0.88 | RAB9A (0.58) | RAB9AKDM4EQPCTLALDH1A1HPGD | |
| SCHEMBL9702773 | 0.87 | RAB9A (0.66) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9704088 | 0.84 | RAB9A (0.61) | RAB9AKDM4EQPCTLQPCTSLC5A2 | |
| SCHEMBL9702249 | 0.83 | RAB9A (0.58) | RAB9AKDM4EQPCTLQPCTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |