Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9704779 | 0.96 | PPARG (0.44) | AGTR1AGTR2PPARG | |
| SCHEMBL9704279 | 0.88 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9704381 | 0.86 | PPARG (0.44) | PPARG | |
| SCHEMBL9704322 | 0.86 | AGTR1 (0.49) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL9042824 | 0.86 | AGTR1 (0.55) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL9704465 | 0.84 | AGTR1 (0.45) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL9704883 | 0.84 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9704406 | 0.83 | PPARG (0.45) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9704812 | 0.81 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9044744 | 0.81 | AGTR1 (0.59) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |