SCHEMBL9704432

SCHEMBL9704432

N#C/C(N)=C(C#N)/N=C/c1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(=O)cc1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.41
MAPT P10636 3/20 0.41
GABRP O00591 3/20 0.33
GABRD O14764 3/20 0.33
GABRA1 P14867 3/20 0.33
GABRB1 P18505 3/20 0.33
GABRG2 P18507 3/20 0.33
GABRB3 P28472 3/20 0.33
GABRA5 P31644 3/20 0.33
GABRA3 P34903 3/20 0.33
GABRA2 P47869 3/20 0.33
GABRB2 P47870 3/20 0.33
GABRA4 P48169 3/20 0.33
GABRE P78334 3/20 0.33
GABRA6 Q16445 3/20 0.33
GABRG1 Q8N1C3 3/20 0.33
GABRG3 Q99928 3/20 0.33
GABRQ Q9UN88 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NR1I2 O75469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704437 1.00 GAA (0.41) GAAMAPTGABRPGABRDGABRA1
SCHEMBL9704596 0.80 GAA (0.42) GAAMAPTGABRPGABRDGABRA1
SCHEMBL9704591 0.80 GAA (0.42) GAAMAPTGABRPGABRDGABRA1
SCHEMBL9704192 0.76 MAPT (0.40) GAAMAPTGABRPGABRDGABRA1
SCHEMBL9704199 0.76 MAPT (0.40) GAAMAPTGABRPGABRDGABRA1
SCHEMBL3198314 0.75 GAA (0.50) GAAMAPTGABRPGABRDGABRA1
SCHEMBL3198319 0.75 GAA (0.50) GAAMAPTGABRPGABRDGABRA1
SCHEMBL9226661 0.75 MAPT (0.50) GAAMAPTGABRA1GABRG2GABRB3
SCHEMBL9226658 0.75 MAPT (0.50) GAAMAPTGABRA1GABRG2GABRB3
SCHEMBL9704972 0.74 GABRP (0.40) GAAMAPTGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013451-A1 IMIDAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-08-20 WO disclosed