Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632622 | 0.98 | GBA1 (0.42) | GBA1MGLLPTGS1PTGS2ALOX5 | |
| SCHEMBL9705943 | 0.92 | MEN1 (0.39) | GBA1ALOX5ALDH1A1GAAMAPT | |
| SCHEMBL5981877 | 0.89 | GBA1 (0.43) | GBA1MGLLPTGS1PTGS2ALOX5 | |
| SCHEMBL5983248 | 0.87 | GBA1 (0.41) | GBA1MGLLPTGS1PTGS2ALOX5 | |
| SCHEMBL993043 | 0.84 | — | — | |
| SCHEMBL5983122 | 0.81 | MEN1 (0.37) | GBA1ALOX5ALDH1A1GAAMAPT | |
| SCHEMBL5621142 | 0.76 | — | — | |
| SCHEMBL5535499 | 0.75 | GBA1 (0.43) | GBA1MGLLPTGS1PTGS2ALOX5 | |
| SCHEMBL9769271 | 0.74 | GBA1 (0.47) | GBA1MGLLPTGS1PTGS2ALOX5 | |
| SCHEMBL9617015 | 0.74 | GBA1 (0.47) | GBA1MGLLPTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |