Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704751 | 1.00 | KDM4E (0.36) | KDM4EKMT2AMEN1NPC1OPRK1 | |
| SCHEMBL9768331 | 0.82 | KDM4E (0.35) | KDM4EKMT2AMEN1NPC1OPRK1 | |
| SCHEMBL9768328 | 0.82 | KDM4E (0.35) | KDM4EKMT2AMEN1NPC1OPRK1 | |
| SCHEMBL10569762 | 0.79 | SRC (0.35) | KDM4EKMT2AMEN1NPC1OPRK1 | |
| SCHEMBL7711320 | 0.78 | TDP1 (0.41) | KDM4EKMT2AMEN1NPC1OPRK1 | |
| SCHEMBL9397605 | 0.74 | TDP1 (0.36) | KDM4EKMT2AMEN1NPC1OPRK1 | |
| SCHEMBL5744936 | 0.73 | MRGPRX4 (0.34) | KDM4EKMT2AMEN1NPC1OPRK1 | |
| SCHEMBL5744932 | 0.73 | MRGPRX4 (0.34) | KDM4EKMT2AMEN1NPC1OPRK1 | |
| SCHEMBL25340703 | 0.73 | NPSR1 (0.46) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL7603528 | 0.73 | KMT2A (0.36) | KDM4EKMT2AHTTGPR35TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013451-A1 | IMIDAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-08-20 | — | — | WO | disclosed |
| US-5064844-A | Miticides | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-11-12 | — | — | US | disclosed |
| CN-1039345-A | TRIAZOLE INSECTICIDES | SCHERING AGROCHEMICALS LTD (GB) | 1990-02-07 | — | — | CN | disclosed |
| EP-0350237-A2 | Triazole insecticides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-01-10 | — | — | EP | disclosed |