Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768331 | 1.00 | KDM4E (0.35) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL9704756 | 0.82 | KDM4E (0.36) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL9704751 | 0.82 | KDM4E (0.36) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL10569762 | 0.78 | SRC (0.35) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL9218250 | 0.76 | GAA (0.33) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL7711320 | 0.76 | TDP1 (0.41) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL9704909 | 0.75 | GAA (0.39) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL9704898 | 0.75 | GAA (0.39) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL9768197 | 0.74 | GAA (0.36) | KDM4EKMT2AHTTNPSR1MEN1 | |
| SCHEMBL9768202 | 0.74 | GAA (0.36) | KDM4EKMT2AHTTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064844-A | Miticides | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-11-12 | — | — | US | disclosed |