Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705244 | 0.96 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9705198 | 0.92 | PPARG (0.41) | — | |
| SCHEMBL9703974 | 0.92 | KDM4E (0.46) | AGTR1AGTR2KDM4EALDH1A1LMNA | |
| SCHEMBL9704516 | 0.90 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9705284 | 0.89 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9704715 | 0.88 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9705918 | 0.87 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9705973 | 0.87 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9704093 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9704128 | 0.86 | KDM4E (0.55) | AGTR1AGTR2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |