SCHEMBL9704852

SCHEMBL9704852

[CH2]Cc1ccccc1Oc1ccc(Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 14/20 0.63
HTR2A P28223 9/20 0.63
SLC6A2 P23975 7/20 0.63
SLC6A3 Q01959 6/20 0.63
PPARA Q07869 1/20 0.51
KCNH2 Q12809 5/20 0.46
HTT P42858 1/20 0.46
SLC1A5 Q15758 1/20 0.46
HRH1 P35367 1/20 0.44
MAPT P10636 1/20 0.44
RIPK1 Q13546 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1202137 0.84 HRH1 (0.60) SLC6A4HTR2ASLC6A2SLC6A3PPARA
SCHEMBL11702925 0.83 SLC6A4 (0.65) SLC6A4HTR2ASLC6A2SLC6A3PPARA
SCHEMBL27483527 0.81 SLC6A4 (0.63) SLC6A4HTR2ASLC6A2SLC6A3PPARA
SCHEMBL641336 0.81 SLC6A4 (0.63) SLC6A4HTR2ASLC6A2SLC6A3PPARA
SCHEMBL4639195 0.81 SLC6A4 (0.63) SLC6A4HTR2ASLC6A2SLC6A3PPARA
SCHEMBL12929642 0.81 SLC6A4 (0.68) SLC6A4HTR2ASLC6A2SLC6A3PPARA
Hydrochloric Acid SCHEMBL9122819 0.80 SLC6A4 (0.61) SLC6A4HTR2ASLC6A2SLC6A3PPARA
SCHEMBL9121785 0.77 SLC6A4 (1.00) SLC6A4HTR2ASLC6A2SLC6A3KCNH2
SCHEMBL8922734 0.77 SLC6A4 (0.62) SLC6A4HTR2ASLC6A2SLC6A3PPARA
SCHEMBL2303574 0.77 SLC6A4 (0.58) SLC6A4HTR2ASLC6A2SLC6A3PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5159117-A Reacting ketone or aldehyde with nitrites in presence of acid catalyst BASF AKTIENGESELLSCHAFT (DE) 1992-10-27 US disclosed