Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.64 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704752 | 0.93 | PPARG (0.60) | PPARGAGTR1AGTR2 | |
| SCHEMBL9705128 | 0.92 | AGTR1 (0.63) | PPARGAGTR1AGTR2 | |
| SCHEMBL9704649 | 0.91 | AGTR1 (0.65) | PPARGAGTR1AGTR2 | |
| SCHEMBL9705281 | 0.89 | AGTR1 (0.66) | PPARGAGTR1AGTR2 | |
| SCHEMBL9704983 | 0.87 | AGTR1 (0.48) | PPARGAGTR1AGTR2 | |
| SCHEMBL9703997 | 0.86 | PPARG (0.54) | PPARGAGTR1AGTR2 | |
| SCHEMBL9704301 | 0.86 | PPARG (0.60) | PPARG | |
| SCHEMBL9704764 | 0.86 | AGTR1 (0.67) | PPARGAGTR1AGTR2 | |
| SCHEMBL9705249 | 0.85 | AGTR1 (0.68) | PPARGAGTR1AGTR2 | |
| SCHEMBL9704108 | 0.84 | AGTR1 (0.69) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |