SCHEMBL9705069

SCHEMBL9705069

CC/C=C/c1cn(C(=O)CC)c(=O)n1Cc1ccc(-c2ccccc2)c(-c2nnn[nH]2)c1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 6/20 0.33
AGTR2 P50052 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9705071 1.00 AGTR1 (0.33) AGTR1AGTR2
SCHEMBL9554491 0.91 AGTR1 (0.38) AGTR1AGTR2
SCHEMBL9554497 0.91 AGTR1 (0.38) AGTR1AGTR2
SCHEMBL9531736 0.84 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL9531739 0.84 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL9706041 0.84 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL9554007 0.83 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL9554004 0.83 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL9704911 0.82 AGTR1 (0.45) AGTR1AGTR2
SCHEMBL9705020 0.81 AGTR1 (0.42) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992007834-A1 N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1992-05-14 WO disclosed