Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333162 | 0.85 | HTT (0.65) | GAAHTTALDH1A1RAB9AMAPT | |
| SCHEMBL4718392 | 0.84 | HTT (1.00) | GAAHTTALDH1A1RAB9AMAPT | |
| SCHEMBL9539274 | 0.83 | HTT (0.54) | GAAHTTALDH1A1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL9388338 | 0.82 | ALDH1A1 (0.65) | GAAHTTALDH1A1RAB9AMAPT | |
| SCHEMBL27782583 | 0.82 | HTT (0.61) | GAAHTTALDH1A1RAB9AMAPT | |
| SCHEMBL9335042 | 0.80 | ALDH1A1 (0.74) | GAAHTTALDH1A1RAB9AMAPT | |
| SCHEMBL16657410 | 0.80 | ALDH1A1 (0.74) | GAAHTTALDH1A1RAB9AMAPT | |
| SCHEMBL16657372 | 0.79 | ALDH1A1 (0.82) | GAAHTTALDH1A1RAB9AMAPT | |
| SCHEMBL4721191 | 0.79 | ALDH1A1 (0.72) | GAAHTTALDH1A1RAB9AMAPT | |
| SCHEMBL4721196 | 0.79 | ALDH1A1 (0.72) | GAAHTTALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014734-A1 | IMIDAZOPYRIDINE PAF/H1 ANTAGONISTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |