Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 9/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963053 | 0.87 | IMPDH2 (0.49) | IMPDH2CYP2A6STING1GPR84IMPDH1 | |
| SCHEMBL28156918 | 0.81 | CYP2A6 (0.50) | IMPDH2CYP2A6STING1GPR84ATM | |
| SCHEMBL28743536 | 0.81 | IMPDH2 (0.44) | IMPDH2CYP2A6STING1GPR84IMPDH1 | |
| SCHEMBL2855201 | 0.81 | MEN1 (0.47) | IMPDH2CYP2A6STING1GPR84IMPDH1 | |
| SCHEMBL28346693 | 0.78 | STING1 (0.49) | IMPDH2CYP2A6STING1GPR84ATM | |
| SCHEMBL6654114 | 0.77 | ATM (0.52) | IMPDH2CYP2A6STING1GPR84IMPDH1 | |
| SCHEMBL22299626 | 0.77 | CYP2A6 (0.49) | IMPDH2CYP2A6STING1GPR84MEN1 | |
| SCHEMBL349436 | 0.76 | MAPK1 (0.51) | PABPC1AHR | |
| SCHEMBL747027 | 0.75 | STING1 (0.55) | IMPDH2CYP2A6STING1GPR84 | |
| SCHEMBL27629215 | 0.75 | NPC1 (0.48) | IMPDH2CYP2A6STING1GPR84IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306650-A | Preparation method of indole carboxamide compound | 西安睿舒维生物医药科技有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-115260080-A | Preparation method of indole-3-carboxamide compound | 浙江理工大学 | 2022-11-01 | — | — | CN | claimed |
| CN-109824574-B | Indole-3-carboxamides and their use | 沈阳药科大学 | 2021-12-28 | — | — | CN | claimed |
| CN-108101828-B | 3-indolyl formamide compound and preparation method thereof | 西华师范大学 | 2021-05-04 | — | — | CN | claimed |
| CN-110475557-A | (R)-N- ((4- methoxyl group-6- methyl-2- oxo-1,2- dihydropyridine-3- base) methyl)-2- methyl-1-(1- (1- (2,2,2- trifluoroethyl) piperidin-4-yl) ethyl) and-1H- indoles-3- formamide solid dispersions | CONSTELLATION PHARMACEUTICALS INC | 2019-11-19 | — | — | CN | claimed |
| CN-110022869-A | For skin and/or the serotonin 1B receptor stimulators of hair reparation | 巴斯德研究院 | 2019-07-16 | — | — | CN | claimed |
| CN-106478662-B | 5-HT3 receptor antagonist | 武田药品工业株式会社 | 2019-07-02 | — | — | CN | claimed |
| CN-109824574-A | Indoles -3- Carbox amide and its application | 沈阳药科大学 | 2019-05-31 | — | — | CN | claimed |
| CN-106946761-B | Indole carboxamides class compound and its application | 沈阳药科大学 | 2019-05-03 | — | — | CN | claimed |
| CN-106459030-B | Replace tropane derivatives | 东亚荣养株式会社 | 2019-01-29 | — | — | CN | claimed |
| CN-108348486-A | 5-hydroxytryptamine 1B receptor agonists as promoters for satellite cell self-renewal and/or differentiation | 巴斯德研究院 | 2018-07-31 | — | — | CN | claimed |
| CN-108329253-A | Preceding neurogenic compounds | 得克萨斯州大学系统董事会 | 2018-07-27 | — | — | CN | claimed |
| CN-105198789-B | Substitute 3- indoles Bcl-2 protein inhibitors and preparation method and application | 山东大学 | 2018-06-05 | — | — | CN | claimed |
| CN-108026073-A | Fluoroindole derivatives as muscarinic M 1 receptor forward direction allosteric modulators | 苏文生命科学有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | claimed |
| CN-105073741-B | Phthalazinones and isoquinolinones as ROCK inhibitors | 百时美施贵宝公司 | 2017-08-08 | — | — | CN | claimed |
| CN-106946761-A | Indole carboxamides class compound and its application | 沈阳药科大学 | 2017-07-14 | — | — | CN | claimed |
| CN-104744460-B | β carbolines, dihydro β carbolines and tetrahydro-beta-carboline alcaloid-derivatives and preparation method thereof and the application in terms of preventing and treating plant virus, sterilization, desinsection | 南开大学 | 2017-06-16 | — | — | CN | claimed |
| CN-119306650-A | Preparation method of indole carboxamide compound | 西安睿舒维生物医药科技有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-5212195-A | Substituted indole antagonists derivatives which are angiotensin II | SYNTEX (U.S.A.) INC. (US) | 1993-05-18 | — | — | US | disclosed |