Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 14/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | HINT1 | P49773 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706215 | 0.92 | TAS1R3 (0.60) | TYMPTAS1R3TAS1R1NT5EHINT1 | |
| SCHEMBL9705378 | 0.90 | TYMP (0.54) | TYMPTAS1R3TAS1R1NT5EHINT1 | |
| SCHEMBL9705652 | 0.89 | TYMP (0.58) | TYMPTAS1R3TAS1R1NT5EHINT1 | |
| SCHEMBL30689445 | 0.88 | TYMP (0.70) | TYMPTAS1R3TAS1R1HINT1IMPDH2 | |
| SCHEMBL34234 | 0.85 | TYMP (0.64) | TYMPTAS1R3TAS1R1NT5EHINT1 | |
| SCHEMBL8613074 | 0.85 | TYMP (0.49) | TYMPNT5E | |
| SCHEMBL9705754 | 0.84 | TYMP (0.54) | TYMPTAS1R3TAS1R1NT5EHINT1 | |
| SCHEMBL9705666 | 0.83 | TYMP (0.58) | TYMP | |
| SCHEMBL6514428 | 0.82 | TYMP (0.57) | TYMPTAS1R3TAS1R1NT5EHINT1 | |
| SCHEMBL30689462 | 0.82 | TYMP (0.53) | TYMPTAS1R3TAS1R1NT5EHINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |