Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705072 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2MME | |
| SCHEMBL9553933 | 0.90 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9705068 | 0.86 | AGTR1 (0.46) | AGTR1AGTR2MME | |
| SCHEMBL9705420 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9530674 | 0.84 | PPARG (0.52) | AGTR1AGTR2 | |
| SCHEMBL9532857 | 0.83 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9535973 | 0.82 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9533140 | 0.80 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9535596 | 0.80 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9555120 | 0.80 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007834-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |