Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821330 | 0.75 | EPHX1 (0.60) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL6518166 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL7318039 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL1323089 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL4358257 | 0.71 | SHBG (0.62) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL9358590 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL3887311 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL3209662 | 0.71 | EPHX1 (0.55) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL11003896 | 0.71 | SHBG (0.62) | EPHX1SHBGTP53LMNACYP2D6 | |
| SCHEMBL454466 | 0.71 | SHBG (0.62) | EPHX1SHBGTP53LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871547-B2 | reducing initial amount of soluble halide in solution of liquid organic medium, viscosity reducing agent, dihydrocarbylmagnesium compound, and the initial amount of soluble halide by mixing alkali metal with solution at mole ratio of metal to magnesium of less than 1:2.5, forming precipitated halide | ALBEMARLE CORPORATION (US) | 2011-01-18 | — | — | US | disclosed |
| EP-1809640-B1 | HALIDE REDUCTION IN DIHYDROCARBYLMAGNESIUM MIXTURES | ALBEMARLE CORP (US) | 2008-07-16 | — | — | EP | disclosed |
| US-20080023856-A1 | Halide Reduction in Dihydrocarbylmagnesium Mixtures | ALBEMARLE CORPORATION (US) | 2008-01-31 | — | — | US | disclosed |
| EP-1809640-A1 | HALIDE REDUCTION DIHYDROCARBYLMAGNESIUM MIXTURES | ALBEMARLE CORPORATION (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006054967-A1 | HALIDE REDUCTION DIHYDROCARBYLMAGNESIUM MIXTURES | ALBEMARLE CORPORATION (US) | 2006-05-26 | — | — | WO | disclosed |