⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27522891 | 1.00 | — | — | |
| SCHEMBL30692032 | 0.73 | — | — | |
| SCHEMBL7450750 | 0.67 | — | — | |
| SCHEMBL4729587 | 0.67 | — | — | |
| SCHEMBL27594923 | 0.65 | — | — | |
| Water SCHEMBL28269400 | 0.65 | — | — | |
| SCHEMBL6415653 | 0.64 | CA1 (0.30) | — | |
| SCHEMBL4697913 | 0.62 | — | — | |
| SCHEMBL25515908 | 0.62 | — | — | |
| SCHEMBL30507521 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1283623-A | 1,2,4,5-tetrahydro-benzo[d] azepine compound | HAFMAN RAROCHE S A F (CH) | 2001-02-14 | — | — | CN | claimed |
| EP-0192034-B1 | DIBENZAZEPINE DERIVATIVES, THEIR PREPARATION, STARTING MATERIALS FOR THEIR PREPARATION, AND USE OF THE DIBENZAZEPINE DERIVATIVES AS PESTICIDES | CIBA-GEIGY AG (CH) | 1992-07-15 | — | — | EP | claimed |
| CN-116981675-A | Degradation of Bruton's Tyrosine Kinase (BTK) by conjugation of BTK inhibitors to E3 ligase ligands and methods of use | 百济神州有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-103635467-A | Fused heterocyclic compounds as modulators of ion channels | GILEAD SCIENCES INC | 2014-03-12 | — | — | CN | disclosed |
| WO-2013026455-A1 | PERMANENTLY POSITIVELY CHARGED ANTIDEPRESSANTS | AARHUS UNIVERSITET (DK) | 2013-02-28 | — | — | WO | disclosed |
| CN-1146455-C | 1,2,4,5-tetrahydro-benzo[d] azepine compound | - | 2004-04-21 | — | — | CN | disclosed |
| CN-1283623-A | 1,2,4,5-tetrahydro-benzo[d] azepine compound | HAFMAN RAROCHE S A F (CH) | 2001-02-14 | — | — | CN | disclosed |