Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.44 |
| ▸ | MME | P08473 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537520 | 0.90 | AGTR1 (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL9706019 | 0.89 | AGTR1 (0.42) | AGTR1AGTR2MMEPPARG | |
| SCHEMBL9036539 | 0.87 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9705196 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9555471 | 0.83 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9705325 | 0.82 | AGTR1 (0.40) | AGTR1AGTR2PPARG | |
| SCHEMBL9555296 | 0.82 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9705512 | 0.81 | FOLH1 (0.41) | AGTR1AGTR2PPARG | |
| SCHEMBL9038808 | 0.81 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9555192 | 0.81 | AGTR1 (0.62) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007834-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |