Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203388 | 0.89 | TSHR (0.67) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL2194321 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMAPTMAOB | |
| SCHEMBL554144 | 0.88 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL30043252 | 0.87 | TSHR (0.64) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6273333 | 0.87 | TSHR (0.64) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9356592 | 0.85 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9158141 | 0.85 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL4456862 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| 3-Nitroaniline SCHEMBL7833209 | 0.83 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAPTMAOB | |
| 3-Nitroaniline SCHEMBL29364768 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KMT2ALMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012118-A1 | PREPARATION OF AROMATIC DIAMINES FROM AMINO PHENOLS OR DIHYDROXYAROMATICS AND BROMOANILINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-23 | — | — | WO | disclosed |