Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172945 | 0.85 | TTR (0.54) | TTRALDH1A1CA2PRSS1 | |
| SCHEMBL9705942 | 0.79 | TTR (0.58) | TTRALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL8354809 | 0.78 | PDE4A (0.52) | TTRMAPTCA2LMNA | |
| SCHEMBL15173216 | 0.78 | TTR (0.50) | TTRCA2PRSS1 | |
| SCHEMBL10854280 | 0.78 | AR (0.51) | ALDH1A1MAPTHPGDL3MBTL1AR | |
| SCHEMBL9705598 | 0.77 | HDAC3 (0.42) | ALDH1A1CA2 | |
| SCHEMBL11331111 | 0.76 | TTR (0.51) | TTRCA2 | |
| SCHEMBL2818338 | 0.76 | S1PR2 (0.54) | TTRSMPD1 | |
| SCHEMBL9077595 | 0.75 | TTR (0.57) | TTRALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL185845 | 0.74 | CA2 (0.68) | TTRALDH1A1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228803-B1 | IONENE ELASTOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-09-16 | — | — | EP | claimed |