Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.48 |
| ▸ | REN | P00797 | 4/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PEPD | P12955 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705671 | 1.00 | ACE (0.48) | ACERENACE2KDM4EF2 | |
| SCHEMBL27953019 | 1.00 | ACE (0.48) | ACERENACE2KDM4EF2 | |
| SCHEMBL29666870 | 0.96 | ACE (0.52) | ACERENACE2KDM4EF2 | |
| SCHEMBL29721089 | 0.94 | CALCRL (0.46) | ACEREN | |
| SCHEMBL29666768 | 0.94 | ACE (0.46) | ACERENACE2KDM4EF2 | |
| SCHEMBL9471485 | 0.93 | ACE (0.48) | ACERENACE2KDM4EF2 | |
| SCHEMBL29666801 | 0.93 | ACE (0.46) | ACERENACE2KDM4EF2 | |
| SCHEMBL29666867 | 0.92 | ACE (0.51) | ACERENACE2KDM4EF2 | |
| SCHEMBL29666873 | 0.91 | ACE (0.44) | ACERENACE2KDM4EF2 | |
| SCHEMBL29666701 | 0.90 | ACE (0.43) | ACERENACE2KDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209643-B1 | PEPTIDE COMPOSITION USEFUL FOR THE MALARIA VACCINE MANUFACTURE AS WELL AS FOR THE PREPARATION OF DIAGNOSTIC KITS FOR THE DETECTION OF MALARIAL DISEASES | ENIRICERCHE S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |
| US-4956449-A | Forming polypeptides from tetrapeptides condensed and separated by chromatography | ENIRICERCHE, S.P.A. (IT) | 1990-09-11 | — | — | US | disclosed |
| EP-0209643-A2 | Peptide composition useful for the malaria vaccine manufacture as well as for the preparation of diagnostic kits for the detection of malarial diseases | ENIRICERCHE S.p.A. (IT) | 1987-01-28 | — | — | EP | disclosed |