Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.46 |
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661451 | 0.94 | MEN1 (0.47) | ACERENMEN1KMT2AKDM4E | |
| SCHEMBL9705671 | 0.93 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL27953019 | 0.93 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL9705665 | 0.93 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL29666768 | 0.91 | ACE (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL29666870 | 0.91 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL30988889 | 0.90 | CALCRL (0.49) | RENF2R | |
| SCHEMBL29666867 | 0.89 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL29794187 | 0.89 | ACE (0.50) | ACERENMEN1KMT2AKDM4E | |
| SCHEMBL29666873 | 0.88 | ACE (0.44) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | ANPEP, NPR3, XPNPEP1 | ACE 900/4885REN 68/4885MEN1 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.