Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 5/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.34 |
| ▸ | KDR | P35968 | 5/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | INSR | P06213 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705933 | 0.95 | VHL (0.42) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL1320486 | 0.78 | VHL (0.47) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL1078939 | 0.78 | MEN1 (0.43) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL9667721 | 0.77 | MEN1 (0.42) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL10262683 | 0.76 | MEN1 (0.44) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL9666007 | 0.75 | NR1I2 (0.41) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL8539204 | 0.75 | NR1I2 (0.41) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL9667987 | 0.75 | NR1I2 (0.41) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL9436389 | 0.75 | NR1I2 (0.41) | VHLMEN1KMT2ANR1I2CYP3A4 | |
| SCHEMBL8875498 | 0.75 | NR1I2 (0.41) | VHLMEN1KMT2ANR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |