Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541695 | 0.88 | RAB9A (0.72) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL9596507 | 0.77 | RAB9A (0.61) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL9596882 | 0.77 | RAB9A (0.76) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL26060354 | 0.77 | RAB9A (0.67) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL11196254 | 0.77 | RAB9A (0.67) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL10392149 | 0.76 | RAB9A (0.70) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL8304745 | 0.75 | CYP1A2 (0.49) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL8300334 | 0.75 | RAB9A (0.50) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL7553424 | 0.75 | RAB9A (0.80) | RAB9ACHRM2LMNACHRM1USP2 | |
| SCHEMBL10968958 | 0.75 | RAB9A (0.68) | RAB9ACHRM2LMNACHRM1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482481-A1 | Method for the preparation of 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepines | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1992-04-29 | — | — | EP | disclosed |