Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704832 | 0.92 | AGTR1 (0.48) | AGTR1AGTR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9704677 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2PPARGCYP1A2CYP3A4 | |
| SCHEMBL9704625 | 0.88 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9703977 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9704842 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9705172 | 0.86 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL9704334 | 0.85 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL9705897 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL9705117 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL9705134 | 0.84 | AGTR1 (0.47) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |