Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704945 | 0.82 | ALDH1A1 (0.44) | HTR1AALDH1A1HTR1BMTNR1A | |
| SCHEMBL9705995 | 0.81 | ALDH1A1 (0.46) | HTR1AALDH1A1HTR1BMTNR1A | |
| SCHEMBL10595250 | 0.80 | ALDH1A1 (0.53) | HTR1AALDH1A1HTR2AGLA | |
| SCHEMBL9705320 | 0.79 | KDM4E (0.43) | HTR1AALDH1A1HTR1B | |
| SCHEMBL9705345 | 0.78 | ALDH1A1 (0.43) | HTR1AALDH1A1HTR1BMTNR1A | |
| SCHEMBL9704794 | 0.78 | ALDH1A1 (0.41) | HTR1AALDH1A1HTR1BMTNR1A | |
| SCHEMBL9706011 | 0.78 | ALDH1A1 (0.52) | HTR1AALDH1A1MTNR1A | |
| SCHEMBL9704917 | 0.78 | ALDH1A1 (0.41) | HTR1AALDH1A1HTR1BMTNR1ATDP2 | |
| SCHEMBL9705343 | 0.76 | MAPT (0.44) | HTR1AALDH1A1 | |
| SCHEMBL9705277 | 0.74 | ALDH1A1 (0.48) | HTR1AALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474323-A1 | Reducing chelants, their complexes with technetium and rhenium, method for their preparation and their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH, c/o FU KLINIKUM RUDOLF VIRCHOW (DE) | 1992-03-11 | — | — | EP | disclosed |