Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.47 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 4/20 | 0.38 |
| ▸ | XPNPEP1 | Q9NQW7 | 3/20 | 0.38 |
| ▸ | LAP3 | P28838 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737851 | 0.82 | ANPEP (0.53) | ANPEPDNPEPSLC7A5PEPDXPNPEP1 | |
| Hydrochloric Acid SCHEMBL737850 | 0.80 | ANPEP (0.51) | ANPEPDNPEPSLC7A5PEPDXPNPEP1 | |
| SCHEMBL7295011 | 0.78 | ANPEP (0.46) | ANPEPDNPEPSLC7A5PEPDXPNPEP1 | |
| SCHEMBL10422730 | 0.78 | METAP2 (0.38) | ANPEPDNPEPTSHRSLC1A3SLC1A2 | |
| SCHEMBL10422698 | 0.78 | METAP2 (0.34) | TSHRMETAP2METAP1 | |
| SCHEMBL15847142 | 0.78 | TSHR (0.36) | ANPEPDNPEPSLC7A5TSHR | |
| SCHEMBL7373706 | 0.78 | TSHR (0.36) | ANPEPDNPEPSLC7A5TSHR | |
| SCHEMBL9514368 | 0.78 | TSHR (0.36) | ANPEPDNPEPSLC7A5TSHR | |
| SCHEMBL770555 | 0.77 | SLC7A5 (0.54) | ANPEPDNPEPSLC7A5LAP3TSHR | |
| SCHEMBL16857258 | 0.77 | SLC7A5 (0.54) | ANPEPDNPEPSLC7A5LAP3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474008-A1 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1992-03-11 | — | — | EP | disclosed |