SCHEMBL9706069

SCHEMBL9706069

CCCCc1c(F)n(Cc2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2)c(-c2nnn[nH]2)c1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 7/20 0.43
AGTR2 P50052 7/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9035607 0.92 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL9705317 0.90 AGTR1 (0.37) AGTR1AGTR2
SCHEMBL9734758 0.90 AGTR1 (0.40) AGTR1AGTR2
SCHEMBL9035641 0.87 AGTR1 (0.50) AGTR1AGTR2
SCHEMBL9532449 0.86 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL9037153 0.86 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL9733915 0.86 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL9705495 0.86 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL9705014 0.86 AGTR1 (0.34) AGTR1AGTR2
SCHEMBL9705028 0.86 AGTR1 (0.41) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992007834-A1 N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1992-05-14 WO claimed