Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.60 |
| ▸ | TOP2A | P11388 | 3/20 | 0.59 |
| ▸ | TERT | O14746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | CASP1 | P29466 | 4/20 | 0.56 |
| ▸ | CASP7 | P55210 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581068 | 0.89 | POLB (0.61) | POLBNPC1GAARAD52RAB9A | |
| SCHEMBL30297107 | 0.89 | POLB (0.61) | POLBNPC1GAARAD52RAB9A | |
| SCHEMBL9706276 | 0.88 | POLB (0.75) | POLBNPC1GAARAD52RAB9A | |
| SCHEMBL9706173 | 0.88 | MAPT (0.64) | POLBNPC1GAARAD52RAB9A | |
| SCHEMBL9706287 | 0.87 | POLB (0.59) | POLBNPC1GAARAD52RAB9A | |
| SCHEMBL9706156 | 0.85 | MAPK1 (0.50) | POLBNPC1GAARAD52RAB9A | |
| SCHEMBL9706260 | 0.85 | MAPT (0.55) | POLBNPC1GAARAD52RAB9A | |
| Foscarnet SCHEMBL9706150 | 0.79 | TOP2A (0.52) | POLBNPC1GAARAD52RAB9A | |
| SCHEMBL27165249 | 0.77 | TOP2A (0.56) | POLBNPC1GAARAD52RAB9A | |
| SCHEMBL9706168 | 0.77 | MAPT (0.70) | POLBNPC1GAARAD52RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |