Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9706065 | 0.87 | MAPT (0.69) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL9706156 | 0.86 | MAPK1 (0.50) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL9706078 | 0.85 | POLB (0.60) | MAPTTDP1L3MBTL1KDM4ECASP1 | |
| SCHEMBL9706173 | 0.84 | MAPT (0.64) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 | |
| Dimethylamine SCHEMBL9706312 | 0.81 | MAPT (0.71) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL24100049 | 0.79 | MAPT (0.49) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL29027271 | 0.76 | MAPT (0.46) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL9706303 | 0.76 | MAPT (0.50) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL24170556 | 0.76 | POLB (0.41) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL1232971 | 0.75 | WEE1 (0.44) | MAPTTDP1L3MBTL1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | claimed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | claimed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | claimed |