Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706156 | 0.90 | MAPK1 (0.50) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL9706137 | 0.89 | MAPK1 (0.63) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL9706117 | 0.87 | MAPK1 (0.47) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL24176382 | 0.85 | POLB (0.43) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL1232971 | 0.85 | WEE1 (0.44) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL30297105 | 0.85 | WEE1 (0.44) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL7636415 | 0.85 | POLB (0.43) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL30297110 | 0.85 | POLB (0.43) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL1581068 | 0.84 | POLB (0.61) | MAPK1ALOX15POLBRAB9ANPC1 | |
| SCHEMBL30297107 | 0.84 | POLB (0.61) | MAPK1ALOX15POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | claimed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | claimed |
| EP-4171561-A1 | 6H-INDOLO[2,3-B]QUINOXALINE DERIVATIVES USEFUL IN THERAPY | Vironova Medical AB (SE) | 2023-05-03 | — | — | EP | disclosed |
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |