Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | CASP1 | P29466 | 4/20 | 0.39 |
| ▸ | CASP7 | P55210 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636415 | 0.85 | POLB (0.43) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL30297105 | 0.85 | WEE1 (0.44) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL9706088 | 0.85 | MAPK1 (0.50) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL30297110 | 0.85 | POLB (0.43) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL1232971 | 0.85 | WEE1 (0.44) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL30297107 | 0.84 | POLB (0.61) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL1581068 | 0.84 | POLB (0.61) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL24170556 | 0.83 | POLB (0.41) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL24170559 | 0.83 | POLB (0.57) | POLBRAB9ANPC1GAARAD52 | |
| SCHEMBL30297099 | 0.83 | POLB (0.57) | POLBRAB9ANPC1GAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312578-A1 | 6H-INDOLO[2,3-B]QUINOXALINE DERIVATIVES USEFUL IN THERAPY | VIRONOVA THIONATION AB (SE) | 2023-10-05 | — | — | US | disclosed |
| WO-2022002898-A1 | 6H-INDOLO(2,3-B)QUINOXALINE DERIVATIVES USEFUL IN THERAPY IN PARTICULAR IN A VIRUS INFECTION | VIRONOVA MEDICAL AB (SE) | 2022-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312578-A1 | 6H-INDOLO[2,3-B]QUINOXALINE DERIVATIVES USEFUL IN THERAPY | IDH3B, IDH3A, IDH1 | POLB 439/4885RAB9A 343/4885NPC1 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.