Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9706065 | 0.81 | MAPT (0.69) | MAPTL3MBTL1TDP1CYP1A2CYP3A4 | |
| Dimethylamine SCHEMBL9706106 | 0.80 | MAPT (0.61) | MAPTL3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL9706144 | 0.79 | TOP2A (0.54) | MAPTL3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL9706276 | 0.75 | POLB (0.75) | MAPTL3MBTL1TDP1TOP2AKDM4E | |
| SCHEMBL9706091 | 0.74 | MAPT (0.44) | MAPTL3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL9706138 | 0.73 | KDM4E (0.46) | MAPTTOP2AKDM4EPOLBRAB9A | |
| SCHEMBL9706173 | 0.72 | MAPT (0.64) | MAPTL3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL9706137 | 0.72 | MAPK1 (0.63) | MAPTL3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL7639668 | 0.72 | POLB (0.55) | MAPTL3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL9706168 | 0.72 | MAPT (0.70) | MAPTL3MBTL1TDP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |