Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | CASP7 | P55210 | 4/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706097 | 0.74 | MAPT (0.49) | MAPTCASP1CASP7HCRTR1KDM4E | |
| SCHEMBL9706134 | 0.72 | ALDH1A1 (0.38) | MAPTCASP1CASP7HCRTR1KDM4E | |
| SCHEMBL9706170 | 0.72 | KMT2A (0.60) | MAPTCASP1CASP7HCRTR1KDM4E | |
| Dimethylamine SCHEMBL9706106 | 0.71 | MAPT (0.61) | MAPTCASP1CASP7HCRTR1KDM4E | |
| SCHEMBL9706165 | 0.71 | KMT2A (0.61) | MAPTCASP1CASP7HCRTR1KDM4E | |
| SCHEMBL9706132 | 0.71 | MAPT (0.51) | MAPTCASP1CASP7HCRTR1KDM4E | |
| SCHEMBL9706303 | 0.70 | MAPT (0.50) | MAPTCASP1CASP7HCRTR1KDM4E | |
| SCHEMBL5530192 | 0.69 | MAPT (0.68) | MAPTCASP1CASP7HCRTR1KDM4E | |
| SCHEMBL8113520 | 0.69 | POLB (0.59) | MAPTCASP1CASP7KDM4ETDP1 | |
| SCHEMBL1581067 | 0.68 | MAPT (0.57) | MAPTCASP1CASP7HCRTR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |