Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.35 |
| ▸ | PI4KA | P42356 | 6/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 6/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11908593 | 0.75 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL5105972 | 0.70 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4455868 | 0.61 | ADORA2A (0.37) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7668705 | 0.61 | ADORA2A (0.41) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL12843997 | 0.60 | ADORA1 (0.56) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL4563686 | 0.60 | ADORA2A (0.41) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL24021884 | 0.59 | ADORA2A (0.39) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL3313637 | 0.59 | HRH2 (0.34) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12844273 | 0.58 | PI4KA (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL72542 | 0.58 | ADORA2A (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |