Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AHCY | P23526 | 5/20 | 0.33 |
| ▸ | PI4KA | P42356 | 3/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435358 | 0.80 | ADORA2A (0.38) | ADORA2AADORA1ADORA2BADORA3AHCY | |
| SCHEMBL22399500 | 0.77 | ADORA2A (0.42) | ADORA2AADORA1ADORA2BADORA3AHCY | |
| SCHEMBL3802731 | 0.77 | AHCY (0.49) | ADORA2AADORA1AHCYPI4KAPI4K2B | |
| SCHEMBL7668705 | 0.75 | ADORA2A (0.41) | ADORA2AADORA1ADORA2BAHCYPI4KA | |
| SCHEMBL72542 | 0.71 | ADORA2A (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL4455868 | 0.71 | ADORA2A (0.37) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL15829723 | 0.71 | ADORA2A (0.37) | ADORA2AADORA1ADORA2BAHCYPI4KA | |
| SCHEMBL667204 | 0.69 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL16949893 | 0.67 | ADORA2A (0.37) | ADORA2AADORA1ADORA2BADORA3AHCY | |
| SCHEMBL1868819 | 0.67 | FDPS (0.44) | ADORA2AADORA1ADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180311237-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | ZPNE GROUP GMBH (CH) | 2018-11-01 | — | — | US | disclosed |
| US-20150031701-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | ZPNE GROUP GMBH (CH) | 2015-01-29 | — | — | US | disclosed |
| EP-2134347-A2 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | Prendergast, Patrick T. (AU) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008110585-A2 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | PRENDERGAST PATRICK T (AU) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180311237-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | SI, MTPN, MUC1 | ADORA2A 1666/4885ADORA1 2214/4885ADORA2B 2650/4885 |
| US-20150031701-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | SI, MTPN, MUC1 | ADORA2A 1666/4885ADORA1 2214/4885ADORA2B 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.