Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855348 | 0.91 | ADRB2 (0.55) | ADRB2ADRB1ADRB3SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL8855375 | 0.90 | ADRB2 (0.56) | ADRB2ADRB1ADRB3SMN1; SMN2KDM4E | |
| SCHEMBL11137221 | 0.84 | ADRB2 (0.51) | CASRADRB2ADRB1ADRB3 | |
| SCHEMBL11132431 | 0.84 | ADRB2 (0.51) | CASRADRB2ADRB1ADRB3 | |
| SCHEMBL8855343 | 0.84 | ADRB2 (0.52) | CASRADRB2ADRB1SMN1; SMN2KDM4E | |
| SCHEMBL10909213 | 0.84 | ADRB2 (0.52) | CASRADRB2ADRB1SMN1; SMN2KDM4E | |
| Bromide SCHEMBL11135620 | 0.83 | ADRB2 (0.50) | CASRADRB2ADRB1ADRB3 | |
| Bromide SCHEMBL8855307 | 0.83 | ADRB2 (0.51) | CASRADRB2ADRB1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL11134717 | 0.83 | ADRB2 (0.53) | CASRADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11134714 | 0.83 | ADRB2 (0.53) | CASRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225165-B1 | USE OF PHENETHANOL AMINES TO IMPROVE FAT CONTENT OF SOWS' MILK | ELI LILLY AND COMPANY (US) | 1992-08-26 | — | — | EP | disclosed |
| US-4904662-A | Raising of pigs | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0225165-A2 | Use of phenethanol amines to improve fat content of sows' milk | ELI LILLY AND COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |