Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | CASP1 | P29466 | 5/20 | 0.72 |
| ▸ | CASP7 | P55210 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | USP2 | O75604 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9436868 | 0.98 | TSHR (0.70) | TSHRMAPTCASP1CASP7POLB | |
| SCHEMBL9706178 | 0.91 | TSHR (0.68) | TSHRMAPTCASP1CASP7POLB | |
| Hydrochloric Acid SCHEMBL9436870 | 0.89 | TSHR (0.67) | TSHRMAPTCASP1CASP7POLB | |
| SCHEMBL5530202 | 0.84 | TSHR (1.00) | TSHRMAPTCASP1CASP7POLB | |
| SCHEMBL15289657 | 0.84 | TSHR (0.72) | TSHRMAPTCASP1CASP7POLB | |
| SCHEMBL13165175 | 0.83 | TSHR (0.70) | TSHRMAPTCASP1CASP7POLB | |
| SCHEMBL5527836 | 0.81 | TSHR (0.83) | TSHRMAPTCASP1CASP7POLB | |
| SCHEMBL9706276 | 0.80 | POLB (0.75) | TSHRMAPTCASP1CASP7POLB | |
| SCHEMBL5524713 | 0.80 | MAPT (1.00) | TSHRMAPTCASP1CASP7POLB | |
| SCHEMBL13888981 | 0.78 | POLB (0.78) | TSHRMAPTCASP1CASP7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |
| WO-1987004437-A1 | INDOLOQUINOXALINES WITH SUBSTITUENTS IN 6-POSITION CONTAINING CYCLIC GROUPS | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |