Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833125 | 0.97 | CYP1A2 (0.50) | CYP1A2CYP1A1CYP1B1ALDH1A1TAAR1 | |
| SCHEMBL28839909 | 0.95 | CYP1A2 (0.48) | CYP1A2CYP1A1CYP1B1ALDH1A1TAAR1 | |
| SCHEMBL3149415 | 0.88 | MMP3 (0.38) | CYP1A2CYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL3076344 | 0.87 | APP (0.57) | CYP1A2CYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL813 | 0.82 | — | — | |
| SCHEMBL20481934 | 0.79 | — | — | |
| SCHEMBL20481942 | 0.79 | — | — | |
| SCHEMBL19810556 | 0.79 | — | — | |
| SCHEMBL20478153 | 0.79 | — | — | |
| SCHEMBL27464368 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3576 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271331-A | Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation | 赣江中药创新中心 | 2024-07-02 | — | — | CN | claimed |
| WO-2024114776-A1 | BICYCLIC ABASIC NUCLEIC ACID ANALOGS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | 上海舶望制药有限公司 | 2024-06-06 | — | — | WO | claimed |
| WO-2024094607-A1 | ISOTOPE LABELED AND NON-LABELED GENTAMICIN C CONGENERS | ROCHE DIAGNOSTICS GMBH (DE) | 2024-05-10 | — | — | WO | claimed |
| US-11912644-B2 | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate | CELGENE CORPORATION (US) | 2024-02-27 | — | — | US | claimed |
| CN-117209395-A | Synthesis method and anticancer activity of selective targeted proliferation cell nuclear antigen drug | 苏州祥沁医疗科技有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117055297-A | Super-resolution laser direct writing method and device based on optical/chemical three-dimensional dark spots | 之江实验室 | 2023-11-14 | — | — | CN | claimed |
| CN-116606338-A | 6' -cyano modified locked nucleosides, nucleotides and nucleic acid polymers | 中国人民解放军军事科学院军事医学研究院 | 2023-08-18 | — | — | CN | claimed |
| US-20230234914-A1 | PROCESSES FOR THE PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE | CELGENE CORPORATION | 2023-07-27 | — | — | US | claimed |
| US-20230183164-A1 | Synthesis of Vinyl Cyclobutyl Intermediates | AMGEN INC. (US) | 2023-06-15 | — | — | US | claimed |
| US-20230174496-A1 | Synthesis of Vinylic Protected Alcohol Intermediates | AMGEN INC. (US) | 2023-06-08 | — | — | US | claimed |
| US-4400393-A | Novel bicyclooctane compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-23 | — | — | US | claimed |
| EP-0075629-A1 | Imidazole derivatives, their preparation, and their pharmaceutical compositions | Sumitomo Chemical Industries Ltd. (JP) | 1983-04-06 | — | — | EP | claimed |
| EP-0012710-B1 | MICROBIOLOGICAL REDUCTION OF 15-KETO-PROSTAGLANDINE INTERMEDIATES | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-02-03 | — | — | EP | claimed |
| US-4283413-A | ANTITUMOR AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1981-08-11 | — | — | US | claimed |
| US-4247635-A | Microbiological reduction of 15-ketoprostaglandin intermediates | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | claimed |
| EP-0012710-A1 | Microbiological reduction of 15-keto-prostaglandine intermediates | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-06-25 | — | — | EP | claimed |
| US-4119718-A | 3-Amino-2-oxy-propoxy-substituted isothiazoles | MERCK & CO., INC. (US) | 1978-10-10 | — | — | US | claimed |
| US-4058665-A | PROSTAGLANDIN, ANTIGASTRIC ULCER | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-11-15 | — | — | US | claimed |
| US-3951964-A | Method for preparing azines | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-04-20 | — | — | US | claimed |
| US-3943132-A | Process for the preparation of hydrazones | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-03-09 | — | — | US | claimed |