Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 3/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649882 | 0.99 | TDP1 (0.49) | TDP1CTSBL3MBTL1POLBALDH1A1 | |
| SCHEMBL9706570 | 0.98 | TDP1 (0.50) | TDP1CTSBL3MBTL1POLBALDH1A1 | |
| SCHEMBL10649877 | 0.89 | TP53 (0.38) | TDP1CTSBL3MBTL1POLBALDH1A1 | |
| SCHEMBL10648522 | 0.85 | KMT2A (0.45) | TDP1CTSBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9706530 | 0.85 | KDM4E (0.48) | POLBALDH1A1KDM4ECMA1TP53 | |
| SCHEMBL9706603 | 0.85 | SLC6A2 (0.37) | TDP1CTSBL3MBTL1POLBALDH1A1 | |
| SCHEMBL9706591 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4ECMA1TP53SMN1; SMN2 | |
| SCHEMBL9706695 | 0.83 | TP53 (0.39) | TDP1CTSBALDH1A1KDM4ECMA1 | |
| SCHEMBL10647260 | 0.83 | SLC6A2 (0.39) | TDP1CTSBL3MBTL1POLBALDH1A1 | |
| SCHEMBL9706537 | 0.81 | TDP1 (0.44) | TDP1CTSBL3MBTL1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |