Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648522 | 0.89 | KMT2A (0.45) | TP53THRBKDM4ESMN1; SMN2CTSB | |
| SCHEMBL10647260 | 0.86 | SLC6A2 (0.39) | TP53THRBKDM4ESMN1; SMN2CTSB | |
| SCHEMBL9706591 | 0.86 | KDM4E (0.51) | TP53KDM4ESMN1; SMN2KMT2ACMA1 | |
| SCHEMBL9706570 | 0.85 | TDP1 (0.50) | TP53THRBKDM4ESMN1; SMN2CTSB | |
| SCHEMBL9706603 | 0.84 | SLC6A2 (0.37) | TP53THRBKDM4ESMN1; SMN2CTSB | |
| SCHEMBL9706530 | 0.84 | KDM4E (0.48) | TP53THRBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9706652 | 0.83 | TDP1 (0.50) | TP53THRBKDM4ESMN1; SMN2CTSB | |
| SCHEMBL9706661 | 0.82 | GABRA1 (0.33) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10649882 | 0.82 | TDP1 (0.49) | TP53THRBKDM4ESMN1; SMN2CTSB | |
| SCHEMBL10649877 | 0.81 | TP53 (0.38) | TP53THRBKDM4ESMN1; SMN2CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |