Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.65 |
| ▸ | CTSB | P07858 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | CASP6 | P55212 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.50 |
| ▸ | MYC | P01106 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262971 | 0.84 | TDP1 (0.55) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9706684 | 0.84 | MAPK1 (0.48) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL1807362 | 0.82 | TDP1 (0.52) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9495720 | 0.81 | TDP1 (0.42) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9796389 | 0.81 | TDP1 (0.42) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL24152419 | 0.81 | TDP1 (0.60) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL29938053 | 0.81 | TDP1 (0.60) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9706598 | 0.80 | TDP1 (0.59) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL13430836 | 0.79 | TDP1 (1.00) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9878734 | 0.79 | HPGD (0.53) | TDP1CTSBALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| EP-0195346-A2 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1986-09-24 | — | — | EP | disclosed |