Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540486 | 0.86 | HPGD (0.49) | HPGDCYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL9877650 | 0.81 | HPGD (0.46) | HPGDCYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL9706679 | 0.79 | TDP1 (0.65) | HPGDCYP1A2POLBTDP1CTSB | |
| SCHEMBL9706684 | 0.77 | MAPK1 (0.48) | HPGDCYP1A2CYP2C19POLBRAB9A | |
| SCHEMBL9263571 | 0.75 | HPGD (0.36) | HPGDCYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL9796389 | 0.74 | TDP1 (0.42) | HPGDCYP1A2POLBTDP1CTSB | |
| SCHEMBL9170693 | 0.72 | HPGD (0.34) | HPGDCYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL9495720 | 0.72 | TDP1 (0.42) | HPGDCYP1A2POLBRAB9ANPC1 | |
| SCHEMBL9796403 | 0.69 | TDP1 (0.38) | HPGDCYP1A2POLBTDP1CTSB | |
| SCHEMBL9877333 | 0.69 | HPGD (0.44) | HPGDCYP1A2CYP3A4CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | claimed |
| EP-0333791-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-09-27 | — | — | EP | claimed |
| WO-1989002891-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-04-06 | — | — | WO | claimed |
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0333791-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-09-27 | — | — | EP | disclosed |
| WO-1989002891-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-04-06 | — | — | WO | disclosed |