Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706598 | 0.84 | TDP1 (0.59) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL9706684 | 0.82 | MAPK1 (0.48) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A | |
| SCHEMBL9706530 | 0.81 | KDM4E (0.48) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A | |
| SCHEMBL9706591 | 0.81 | KDM4E (0.51) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A | |
| SCHEMBL10648622 | 0.80 | CYP4F2 (0.41) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A | |
| SCHEMBL10645317 | 0.79 | CYP4F2 (0.47) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A | |
| SCHEMBL6699195 | 0.78 | CYP4F2 (0.44) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A | |
| SCHEMBL10650710 | 0.78 | BAZ2B (0.54) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A | |
| SCHEMBL25776569 | 0.75 | CYP4F2 (0.40) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A | |
| SCHEMBL10644841 | 0.73 | SMN1; SMN2 (0.54) | MAPK1CYP4F2CYP4A11BAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |