Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 19/20 | 0.62 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957099 | 0.97 | LTB4R (0.66) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821851 | 0.90 | LTB4R (0.72) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8957196 | 0.90 | LTB4R (0.73) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8957195 | 0.89 | LTB4R (0.63) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8957078 | 0.86 | LTB4R (0.76) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8941350 | 0.84 | LTB4R (0.88) | LTB4RLTB4R2 | |
| SCHEMBL9198930 | 0.84 | LTB4R (0.75) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9196413 | 0.84 | LTB4R (0.64) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8957165 | 0.83 | LTB4R (0.87) | LTB4RLTB4R2 | |
| SCHEMBL8957064 | 0.83 | LTB4R (0.75) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000011-A2 | LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-01-09 | — | — | WO | disclosed |