Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 8/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195871 | 0.92 | LTB4R (0.49) | LTB4RLTB4R2CYSLTR2CYSLTR1LMNA | |
| SCHEMBL8941387 | 0.87 | CYSLTR2 (0.59) | LTB4RLTB4R2CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9196138 | 0.86 | LTB4R (0.57) | LTB4RLTB4R2CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9196144 | 0.86 | LTB4R (0.60) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8941560 | 0.79 | CYSLTR2 (0.51) | LTB4RLTB4R2CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9192886 | 0.79 | LTB4R (0.52) | LTB4RLTB4R2CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9192882 | 0.79 | LTB4R (0.50) | LTB4RLTB4R2CYSLTR2CYSLTR1LMNA | |
| SCHEMBL8941565 | 0.79 | LTB4R (0.56) | LTB4RLTB4R2CYSLTR2CYSLTR1LMNA | |
| SCHEMBL6933646 | 0.77 | LTB4R (0.52) | LTB4RLTB4R2LMNAMAPTHDAC6 | |
| SCHEMBL8777242 | 0.76 | CYSLTR2 (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000011-A2 | LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-01-09 | — | — | WO | claimed |