SCHEMBL9706881

SCHEMBL9706881

CCCCCCCCOCC1([SiH3])CCCCO1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CES2 O00748 2/20 0.36
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
THRB P10828 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
ASGR1 P07306 2/20 0.33
SCN2A Q99250 2/20 0.32
USP2 O75604 1/20 0.31
CES1 P23141 1/20 0.30
SPHK2 Q9NRA0 1/20 0.30
SPHK1 Q9NYA1 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14699479 0.98 ALDH1A1 (0.35) ALDH1A1TDP1CES2HTTMEN1
SCHEMBL9986320 0.81
SCHEMBL9308300 0.81 TSHR (0.33) ALDH1A1TDP1HTTMEN1THRB
SCHEMBL4517435 0.80 SCN2A (0.34) SCN2A
SCHEMBL8509327 0.80 SCN2A (0.34) SCN2A
SCHEMBL6517289 0.80 SCN2A (0.34) SCN2A
SCHEMBL9237635 0.80 SCN2A (0.34) SCN2A
SCHEMBL2457674 0.80 SCN2A (0.34) SCN2A
SCHEMBL8610591 0.80 SCN2A (0.34) SCN2A
SCHEMBL598640 0.80 SCN2A (0.34) SCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11525962-B2 Optical fiber alignment device with self-healing refractive index-matching gel of polysiloxane and method of making COMMSCOPE TECHNOLOGIES LLC (US) 2022-12-13 US disclosed
US-20210356676-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2021-11-18 US disclosed
US-11054583-B2 Optical fiber alignment device with self-healing refractive index-matching gel COMMSCOPE TECHNOLOGIES LLC (US) 2021-07-06 US disclosed
US-20200116947-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2020-04-16 US disclosed
EP-3635461-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL Commscope Technologies LLC (US) 2020-04-15 EP disclosed
WO-2018226872-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2018-12-13 WO disclosed
US-5079300-A Curable Gel RAYCHEM CORPORATION (US) 1992-01-07 US disclosed
EP-0461185-A1 METHOD OF CURING ORGANOPOLYSILOXANE COMPOSITIONS AND COMPOSITIONS AND ARTICLES THEREFROM RAYCHEM CORPORATION (US) 1991-12-18 EP disclosed
WO-1990010035-A1 METHOD OF CURING ORGANOPOLYSILOXANE COMPOSITIONS AND COMPOSITIONS AND ARTICLES THEREFROM RAYCHEM CORPORATION (US) 1990-09-07 WO disclosed