Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octyldodecanol SCHEMBL2247437 | 0.84 | LMNA (0.62) | LMNAPRSS1PRSS2PRSS3CSNK1E | |
| Heptane SCHEMBL3728317 | 0.80 | LMNA (0.55) | LMNAALDH1A1TSHRALOX12ACHE | |
| SCHEMBL22129684 | 0.80 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL22129715 | 0.80 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL22129706 | 0.80 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL23926839 | 0.80 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL25256897 | 0.80 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL23926893 | 0.80 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL22129671 | 0.80 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL23362895 | 0.80 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132115-A | PLANAR THERAPEUTIC SYSTEM, PROCESS FOR ITS PRODUCTION AND UTILIZATION | LOHMANN GMBH & CO., KG, A GERMAN CORP. (DE) | 1992-07-21 | — | — | US | disclosed |
| EP-0242827-B1 | SURFACE SHAPED THERAPEUTIC SYSTEM, METHOD FOR ITS MANUFACTURE, AND ITS APPLICATION | Lohmann GmbH & Co. KG (DE) | 1991-12-27 | — | — | EP | disclosed |
| EP-0242827-A1 | Surface shaped therapeutic system, method for its manufacture, and its application | Lohmann GmbH & Co. KG (DE) | 1987-10-28 | — | — | EP | disclosed |
| WO-1987006144-A1 | PLANAR THERAPEUTIC SYSTEM, PROCESS FOR ITS PRODUCTION AND ITS UTILIZATION | LOHMANN GMBH & CO. KG. (DE) | 1987-10-22 | — | — | WO | disclosed |