Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145937 | 1.00 | TSHR (0.50) | TSHRTDP1L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL17942873 | 0.98 | TSHR (0.49) | TSHRTDP1L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL18663388 | 0.86 | TSHR (0.51) | TSHRTDP1L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL1274391 | 0.84 | TSHR (0.50) | TSHRTDP1L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL12443327 | 0.83 | THRB (0.53) | TSHRTDP1L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL13539403 | 0.83 | TSHR (0.49) | TSHRTDP1L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL18663316 | 0.81 | TSHR (0.53) | TSHRTDP1L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL19690589 | 0.80 | TSHR (0.54) | TSHRTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL18663315 | 0.80 | TSHR (0.54) | TSHRTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL18663248 | 0.80 | TSHR (0.54) | TSHRTDP1L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013861-A1 | HERBICIDAL BICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-20 | — | — | WO | disclosed |
| WO-1992010501-A1 | HERBICIDAL ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992009587-A1 | HERBICIDAL OXAZINE ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009578-A1 | SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |