Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027226 | 0.88 | PDE3B (0.37) | NPC1MAPTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL27901873 | 0.84 | PDGFRB (0.46) | PDGFRBPDGFRAMAPTLMNAPDE3B | |
| SCHEMBL20208508 | 0.83 | CA1 (0.45) | PDGFRBPDGFRAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL147112 | 0.83 | PDGFRB (0.35) | PDGFRBPDGFRAALPLPDE3BPDE3A | |
| SCHEMBL8599616 | 0.81 | MEN1 (0.46) | PDGFRBPDGFRAMAPTPDE3BPDE3A | |
| SCHEMBL30159393 | 0.81 | PDGFRB (0.49) | PDGFRBPDGFRANPC1MAPTRAB9A | |
| SCHEMBL20260273 | 0.80 | KMT2A (0.42) | PDGFRBPDGFRAMAPTLMNASMN1; SMN2 | |
| SCHEMBL20260490 | 0.80 | PDGFRB (0.43) | PDGFRBPDGFRAMAPTMEN1KMT2A | |
| SCHEMBL30159185 | 0.79 | THRB (0.39) | PDGFRBPDGFRAFGFR1 | |
| SCHEMBL204478 | 0.79 | MEN1 (0.47) | PDGFRBPDGFRANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022536-A1 | VINYLIMIDAZOLES, VINYLTRIAZOLES AND VINYLTETRAZOLES WITH A BICYCLIC SUBSTITUENT GROUP | SCHERING AKTIENGESELLSCHAFT, BERLIN UND BERGKAMEN (DE) | 1992-12-23 | — | — | WO | disclosed |
| EP-0518457-A1 | Bicyclic substituted vinylimidazoles, -triazoles and -tetrazoles | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-16 | — | — | EP | disclosed |