SCHEMBL970730

SCHEMBL970730

[SiH3]CCC(Cl)CCCCCCCl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6751593 1.00 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL9108099 1.00 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL4429606 1.00 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL1719880 0.97 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL29105368 0.87 TSHR (0.40) ALDH1A1TSHR
SCHEMBL15541793 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL8665942 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL5323576 0.79
SCHEMBL1446445 0.78 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL9734937 0.76 TSHR (0.36) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000092-B2 Rubber composition comprising a blocked mercaptosilane coupling agent COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-04-07 US disclosed
EP-2379633-B1 RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT MICHELIN & CIE (FR) 2014-05-07 EP disclosed
US-20110306700-A1 RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT MICHELIN RECHERCHE ET TECHNIQUE S.A. (SE) 2011-12-15 US disclosed
EP-2379633-A1 RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT Société de Technologie MICHELIN (FR) 2011-10-26 EP disclosed
US-20110009547-A1 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2011-01-13 US disclosed
EP-2212379-A2 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT Société de Technologie MICHELIN (FR) 2010-08-04 EP disclosed
WO-2010072682-A1 RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2010-07-01 WO disclosed
WO-2009062733-A2 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2009-05-22 WO disclosed